CHEMBRDG-BB 4011481

CHEMBRDG-BB 4011481 - Names and Identifiers

Name	[4-(1H-pyrazol-1-yl)phenyl]boronic acid
Synonyms	AKOS P-2123527 VITAS-BB TBB011770 ART-CHEM-BB B037013 CHEMBRDG-BB 4011481 4-PYRAZOL-1-YL-PHENYLBORONIC ACID [4-(1H-pyrazol-1-yl)phenyl]boronic acid [4-(1H-PYRAZOL-1-YL)PHENYL]BORONIC ACID boronic acid, [4-(1H-pyrazol-1-yl)phenyl]- boronic acid, B-[4-(1H-pyrazol-1-yl)phenyl]-
CAS	891270-35-2
InChI	InChI=1/C9H9BN2O2/c13-10(14)8-2-4-9(5-3-8)12-7-1-6-11-12/h1-7,13-14H

CHEMBRDG-BB 4011481 - Physico-chemical Properties

Molecular Formula	C9H9BN2O2
Molar Mass	187.99
Density	1.209g/cm³
Boling Point	374.051°C at 760 mmHg
Flash Point	180.02°C
Vapor Presure	0mmHg at 25°C
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.59

CHEMBRDG-BB 4011481 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection.
Hazard Class	IRRITANT

CHEMBRDG-BB 4011481 - Introduction

[4-(1H-pyrazol-1-yl)phenyl]boronic is an organic boron compound with the chemical formula C10H9BN2O2.

Nature:
[4-(1H-pyrazol-1-yl)phenyl]boronic acid is a white to light yellow solid with a melting point of about 180-183°C, soluble in some organic solvents such as dimethyl sulfoxide and acetonitrile. It is stable under acidic conditions, but decomposes under alkaline conditions.

Use:
The compound has important application value in organic synthesis, especially in the aromatic coupling reaction. It is often used as a ligand or catalyst, and can be used in the synthesis of organic compounds containing aryl borate, such as drugs, natural product synthesis, etc.

Preparation Method:
The preparation of [4-(1H-pyrazol-1-yl)phenyl]boronic acid can be achieved by the reaction of pyrazole and phenylboronic acid. A common method is to add the pyrazole to the phenylboronic acid and then treat it under acidic conditions to obtain the desired product.

Safety Information:
[4-(1H-pyrazol-1-yl)phenyl]boronic acid is safe, but care should be taken to prevent inhalation, swallowing and contact with skin. Wear protective gloves and glasses when using or handling, and ensure that the operation is carried out in a well-ventilated place. Hazardous substances may be produced when in contact with strong alkalis, so mixing with alkalis should be avoided. If necessary, refer to the relevant safety manual or consult a professional.

Last Update：2024-04-09 20:44:15